The Applied Microbiology Laboratory of a Japanese university has officially put into use the ceramic membrane filtration system specially customized by our company. This equipment has been successfully applied in the precise sterilization process of yeast extract, providing an unprecedented purity guarantee for academic research.
Research Background
The ongoing research project on "Secondary Metabolites of yeast" at a Japanese university is facing key challenges:
The traditional filtration method leads to a loss rate of the target product as high as 40%
The current system is unable to completely remove contaminants smaller than 0.5μm
Manual operation is prone to cause sample contamination
Technical solution
The special filtration system provided by our company features
Core configuration
Food-grade SS304 mirror-polished main body (Ra≤0.4μm)
19-channel ceramic membrane filter element (Φ25×1016mm)
0.2μm precision filtration accuracy
Fully enclosed 3/8-inch sanitary interface
Technological breakthrough
Multi-channel ceramic membrane: 19 3.5mm channels achieve high-throughput filtration
Mirror polishing process: Surface roughness < 0.8μm, preventing microbial adhesion
Modular design: Each filter element has a filtration area of 0.25 square meters and can be flexibly expanded
Integrity test: Supports online bubble point detection (> 0.3MPa)
Comparison of experimental data
The improvement effect of the traditional parameter method ceramic membrane system
Filtration time: 120 minutes - 45 minutes -62.5%
Residual miscellaneous bacteria: 10³CFU/mL < 1CFU/mL > 99.9%
The product yield is 58% to 92% and 58.6% respectively
Repeatability CV > 15% CV < 3% -80%
System Features
• Complies with the aseptic requirements of JP/USP
• Resistant to online sterilization at 121℃
• Supports reverse flushing regeneration
• Fully traceable records throughout the entire process
User feedback
"The performance of this system far exceeded expectations," said Professor Yamamoto, the project leader. "Its filtration accuracy of 0.2μm enabled us to obtain experimental data free from the interference of contaminants for the first time, and the recovery rate of yeast active components increased to over 95%."
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